Domoic acid
Tocris Bioscience | Catalog # 0269
Key Product Details
Description
Product Description
Domoic acid is a kainate receptor agonist. More potent and possibly more selective than kainate at kainate receptors, as demonstrated in electrophysiological studies.
Product Specifications for Domoic acid
Molecular Weight
Formula
Storage
Purity
Chemical Name
CAS Number
PubChem ID
InChI Key
SMILES
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 15.57 | 50 |
Preparing Stock Solutions for Domoic acid
The following data is based on the product molecular weight 311.33.
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.5 mM | 6.42 mL | 32.12 mL | 64.24 mL |
| 2.5 mM | 1.28 mL | 6.42 mL | 12.85 mL |
| 5 mM | 0.64 mL | 3.21 mL | 6.42 mL |
| 25 mM | 0.13 mL | 0.64 mL | 1.28 mL |
Calculators
Background References
References are publications that support the biological activity of the product. See our Citations tab to view 4 publications citing the usage of this product.
- Hampson and Manalo The activation of glutamate receptors by kainic acid and domoic acid. Nat.Toxins 1998 PMID: 10223631
- Debonnel Domoic acid, the alleged 'mussel toxin', might produce its neurotoxic effect through kainate receptor activation: an electro-physiological study in rat dorsal hippocampus. Can.J.Physiol.Pharmacol. 1989 PMID: 2540893
- Watkins Experiments with kainate and quisqualate agonists and antagonists in relation to the sub-classification of 'non-NMDA' receptors. Excitatory Amino Acids and Synaptic Plasticity. Ed
- Agrawal and Evans The primary afferent depolarizing action of kainate in the rat. Br.J.Pharmacol. 1986 PMID: 3513882
Product Documents for Domoic acid
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for Domoic acid
For research use only
Citations for Domoic acid
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