dTAG-Biotin

Tocris Bioscience | Catalog # 7883

Affinity probe for mutant FKBP12F36V proteins
Tocris Bioscience

Key Product Details

Description

Affinity probe for mutant FKBP12F36V proteins
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Product Description

dTAG-Biotin is an affinity probe for mutant FKBP12F36V proteins. Comprises the ligand ortho-AP1867, selective for F36V single-point mutated FKBP12, joined by a PEG3 linker to biotin. It can be used for chemical biology studies such as proteomics, enrichment studies, dimerization experiments, and assay validation.

Product Specifications for dTAG-Biotin

Molecular Weight

1094.33

Formula

C56H79N5O15S

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

(R)-3-(3,4-Dimethoxyphenyl)-1-(2-((2,16-dioxo-20-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-6,9,12-trioxa-3,15-diazaicosyl)oxy)phenyl)propyl (S)-1-((S)-2-(3,4,5-trimethoxyphenyl)butanoyl)piperidine-2-carboxylate

InChI Key

ZUFVYPUCFFRQTG-ZFJGIIHNSA-N

SMILES

CC[C@@H](C1=CC(OC)=C(C(OC)=C1)OC)C(N2CCCC[C@H]2C(O[C@@H](C3=CC=CC=C3OCC(NCCOCCOCCOCCNC(CCCC[C@@H]4SC[C@@](N5)([H])[C@]4([H])NC5=O)=O)=O)CCC6=CC(OC)=C(C=C6)OC)=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 109.43 100

Preparing Stock Solutions for dTAG-Biotin

The following data is based on the product molecular weight 1094.33.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 0.91 mL 4.57 mL 9.14 mL
5 mM 0.18 mL 0.91 mL 1.83 mL
10 mM 0.09 mL 0.46 mL 0.91 mL
50 mM 0.02 mL 0.09 mL 0.18 mL

Calculators

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

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Background References

References are publications that support the biological activity of the product.

Product Documents for dTAG-Biotin

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for dTAG-Biotin

For research use only

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