Recombinant Human DTD1 His Protein

Novus Biologicals | Catalog # NBP2-23008

Novus Biologicals
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Key Product Details

Source

E. coli

Tag

His

Applications

SDS-PAGE
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Product Specifications

Description

A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-209 of Human DTD1

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSMKAVVQR VTRASVTVGG EQISAIGRGI CVLLGISLED TQKELEHMVR KILNLRVFED ESGKHWSKSV MDKQYEILCV SQFTLQCVLK GNKPDFHLAM PTEQAEGFYN SFLEQLRKTY RPELIKDGKF GAYMQVHIQN DGPVTIELES PAPGTATSDP KQLSKLEKQQ QRKEKTRAKG PSESSKERNT PRKEDRSASS GAEGDVSSER EP

Purity

>85%, by SDS-PAGE

Predicted Molecular Mass

25.9 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human DTD1 His Protein

SDS-PAGE: Recombinant Human DTD1 His Protein [NBP2-23008]

SDS-PAGE: Recombinant Human DTD1 His Protein [NBP2-23008]

SDS-Page: DTD1 Protein [NBP2-23008]

Formulation, Preparation, and Storage

NBP2-23008
Formulation 20 mM Tris-HCl buffer (pH 8.0), 0.1 M NaCl, 10% glycerol, 1 mM DTT
Preservative No Preservative
Concentration 0.5 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: DTD1

DTD1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). It could be a defense mechanism against a harmful effect of D-tyrosine. DTD1 may be a risk factor for aspirin-intolerant asthma (AIA) by catalyzing the hydrolysis of D-tryptophan and interacting with the tyrosyl-tRNA synthetase (tyrRS) enzyme, which promotes a pro-inflammatory phenotype. This protein is localize to the DUE(DNA unwinding element )s of active replication origins. Recombinant human DTD1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Alternate Names

bA379J5.3, bA555E18.1, C20orf88HARS2, chromosome 20 open reading frame 88, DNA-unwinding element-binding protein, D-tyrosyl-tRNA deacylase 1 homolog (S. cerevisiae), D-tyrosyl-tRNA(Tyr) deacylase 1, DUEB, EC 3.1, Histidyl-tRNA synthase-related, histidyl-tRNA synthetase 2, MGC119131, MGC41905, pqn-68

Gene Symbol

DTD1

Additional DTD1 Products

Product Documents for Recombinant Human DTD1 His Protein

Certificate of Analysis

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Product Specific Notices for Recombinant Human DTD1 His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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