Dynole 34-2

Tocris Bioscience | Catalog # 4222

Dynamin I inhibitor
Tocris Bioscience

Key Product Details

Description

Dynamin I inhibitor
View all Dynamin Inhibitors »

Product Description

Dynole 34-2 is a dynamin I inhibitor (IC50 = 1.3 μM). Inhibits receptor-mediated endocytosis (RME) (IC50 = 5.0 μM).

Product Specifications for Dynole 34-2

Molecular Weight

408.58

Formula

C25H36N4O

Storage

Store at +4°C

Purity

≥98% (HPLC)

Chemical Name

2-Cyano-3-[1-[3-(dimethylamino)propyl]-1H-indol-3-yl]-N-octyl-2-propenamide

CAS Number

1128165-88-7

PubChem ID

44157463

InChI Key

MYIMRONQBLZJFI-DYTRJAOYSA-N

SMILES

CN(C)CCCN2C1=CC=CC=C1C(/C=C(C(NCCCCCCCC)=O)\C#N)=C2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 40.86 100
Ethanol 20.43 50

Preparing Stock Solutions for Dynole 34-2

The following data is based on the product molecular weight 408.58.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.45 mL 12.24 mL 24.48 mL
5 mM 0.49 mL 2.45 mL 4.90 mL
10 mM 0.24 mL 1.22 mL 2.45 mL
50 mM 0.05 mL 0.24 mL 0.49 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 12 publications citing the usage of this product.

Product Documents for Dynole 34-2

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Dynole 34-2

For research use only

Customer Reviews for Dynole 34-2 (1)

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  • Dynamin inhibitor
    Name: Timothy Ryan
    Species: Rat
    Assay Type: In Vitro
    Cell Line/Tissue: Primary hippocampal neurons
    Verified Customer | Posted 06/20/2025
    The drug was incubated at 15 μM to inhibit Dynamin function.

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