ERB 041

Key Product Details

Product Description

ERB 041 is a potent ERβ agonist; displays >200-fold selectivity for ERβ over ERα (IC₅₀ values are 5 and 1216 nM for human ERβ and ERα; 3.1 and 620 nM for rat ERβ and ERα; and 3.7 and 750 nM for mouse ERβ and ERα respectively).

Licensing Information

Sold for research purposes under agreement from Pfizer Inc.

Product Specifications for ERB 041

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for ERB 041

The following data is based on the product molecular weight 271.24.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.69 mL	18.43 mL	36.87 mL
5 mM	0.74 mL	3.69 mL	7.37 mL
10 mM	0.37 mL	1.84 mL	3.69 mL
50 mM	0.07 mL	0.37 mL	0.74 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 12 publications citing the usage of this product.

• Malamas Design and synthesis of aryl diphenolic azoles as potent and selective estrogen receptor-β ligands. J.Med.Chem. 2004 PMID: 15456246
• Cvoro Selective estrogen receptor-γ agonists repress transcription of proinflammatory genes. J.Immunol. 2008 PMID: 18097065
• Harris Evaluaton of an estrogen receptor-β agonist in animal models of human disease. Endocrinology 2003 PMID: 14500559

Product Documents for ERB 041