FCCP

Tocris Bioscience | Catalog # 0453

Oxidative phosphorylation uncoupler
Tocris Bioscience

Key Product Details

Description

Oxidative phosphorylation uncoupler
View all Oxidative Phosphorylation Uncouplers »

Product Description

FCCP is a very potent uncoupler of oxidative phosphorylation in mitochondria.

Product Specifications for FCCP

Molecular Weight

254.17

Formula

C10H5F3N4O

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

Carbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone

CAS Number

370-86-5

PubChem ID

3330

InChI Key

BMZRVOVNUMQTIN-UHFFFAOYSA-N

SMILES

N#CC(C#N)=NNC1=CC=C(OC(F)(F)F)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 25.42 100

Preparing Stock Solutions for FCCP

The following data is based on the product molecular weight 254.17.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.93 mL 19.67 mL 39.34 mL
5 mM 0.79 mL 3.93 mL 7.87 mL
10 mM 0.39 mL 1.97 mL 3.93 mL
50 mM 0.08 mL 0.39 mL 0.79 mL

Calculators

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

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The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 94 publications citing the usage of this product.

Product Documents for FCCP

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for FCCP

For research use only

Customer Reviews for FCCP (2)

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  • We got expected effect on cells
    Name: Anonymous
    Species: Mouse
    Assay Type: In Vitro
    Cell Line/Tissue: Primary pancreatic ductal epithelial cells
    Verified Customer | Posted 04/03/2020
    4 μM FCCP
    FCCP 0453
  • Mitochondrial bioenergetics measurements by reagent screen
    Name: Anonymous
    Species: Mouse
    Assay Type: In Vitro
    Cell Line/Tissue: mouse brain endothelioma cell line
    Verified Customer | Posted 03/15/2020
    1 μM
    FCCP 0453

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