Felodipine

Tocris Bioscience | Catalog # 2960

CaV1.x blocker
Tocris Bioscience
Discontinued Product
2960 has been discontinued. View all Cav1.x Channel Blockers products.

Key Product Details

Description

CaV1.x blocker
View all Cav1.x Channel Blockers »

Product Description

Felodipine is a L-type Ca2+ channel blocker that is selective over N-, R-, P/Q- and T-type channels. Displays high vascular selectivity; lowers arterial blood pressure without altering cardiac contractility. Antihypertensive.

Product Specifications for Felodipine

Molecular Weight

384.25

Formula

C18H19Cl2NO4

Storage

Store at +4°C

Purity

≥98% (HPLC)

Chemical Name

4-(2,3-Dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid ethyl methyl ester

CAS Number

72509-76-3

PubChem ID

3333

InChI Key

RZTAMFZIAATZDJ-UHFFFAOYSA-N

SMILES

ClC1=C(Cl)C(C2C(C(OC)=O)=C(C)NC(C)=C2C(OCC)=O)=CC=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 38.42 100
Ethanol 38.42 100

Preparing Stock Solutions for Felodipine

The following data is based on the product molecular weight 384.25.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.60 mL 13.01 mL 26.02 mL
5 mM 0.52 mL 2.60 mL 5.20 mL
10 mM 0.26 mL 1.30 mL 2.60 mL
50 mM 0.05 mL 0.26 mL 0.52 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for Felodipine

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Felodipine

For research use only

Related Research Areas

Ion Channels and Regulators

Customer Reviews for Felodipine (1)

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  • Felodipine used on Cav1.2 channels
    Name: Anonymous
    Species: Human
    Verified Customer | Posted 02/04/2019
    Felodipine used on Cav1.2 channels to see the effect on blocking with increasing concentration and the underlying mechanism involved.
    Felodipine 2960

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