FFN 270
Tocris Bioscience | Catalog # 6717
Key Product Details
Description
Product Description
FFN 270 is a fluorescent false neurotransmitter (FFN). Fluorescent substrate for NET and VMAT2. Labels noradrenergic neurons and their synaptic vesicles, and enables imaging of synaptic vesicle content release from specific axonal sites in vivo. Selectively labels NA neurons over other monoamine and CNS targets. Exhibits two resolved absorption/excitation maxima depending on solvent pH (excitation maxima: 320 nm or 365 nm, emission maxima: 475 nm).Scientific Data Images for FFN 270
Amphetamine-stimulated release of FFN 270 from noradrenergic projections.
Amphetamine releases FFN 270 from noradrenergic projections in vivo. Images show FFN 270 puncta in Layer 1 of the barrel cortex in mice taken before (left) and after injection (right) of amphetamine (AMPH).Licensing Information
Sold with the permission of Columbia University.Spectra Viewer
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Product Specifications for FFN 270
Molecular Weight
Formula
Storage
Purity
Chemical Name
CAS Number
SMILES
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 25.97 | 100 |
Preparing Stock Solutions for FFN 270
The following data is based on the product molecular weight 259.66.
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 3.85 mL | 19.26 mL | 38.51 mL |
| 5 mM | 0.77 mL | 3.85 mL | 7.70 mL |
| 10 mM | 0.39 mL | 1.93 mL | 3.85 mL |
| 50 mM | 0.08 mL | 0.39 mL | 0.77 mL |
Calculators
Background References
References are publications that support the biological activity of the product.
- Dunn Designing a norepinephrine optical tracer for imaging individual noradrenergic synapses and their activity in vivo. Nat.Commun. 2018 PMID: 30026491
Product Documents for FFN 270
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for FFN 270
For research use only
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