FSLLRY-NH2
Tocris Bioscience | Catalog # 4751
Key Product Details
Description
Product Description
FSLLRY-NH2 is a selective PAR2 peptide antagonist. Reverses taxol-induced mechanical allodynia, heat hyperalgesia and PKC activation in ICR mice. Blocks ERK activation and collagen production in isolated cardiac fibroblasts. Also reduces symptoms in a mouse model of dermatophyte-associated itch. FSLLRY-NH2 inhibits C. albicans induced inflammation in oral mucosal cells in vitro.
Product Specifications for FSLLRY-NH2
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The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solubility | Soluble to 1mg/ml in water |
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Background References
References are publications that support the biological activity of the product. See our Citations tab to view 33 publications citing the usage of this product.
- Kumar Candida albicans Sap6 initiates oral mucosal inflammation via the protease activated receptor PAR2. Front.Immunol. 2022 PMID: 35844627
- Chen Proteinase-activated receptor 2 sensitizes transient receptor potential vanilloid 1, transient receptor potential vanilloid 4, and transient receptor potential ankyrin 1 in PacT.-induced neuropathic pain. Neuroscience 2011 PMID: 21763756
- Andoh Involvement of serine protease and proteinase-activated receptor 2 in dermatophyte-associated itch in mice. J.Pharmacol.Exp.Ther. 2012 PMID: 22761302
- McLarty Tryptase/protease-activated receptor 2 interactions induce selective mitogen-activated protein kinase signaling and collagen synthesis by cardiac fibroblasts. Hypertension 2011 PMID: 21730297
Product Documents for FSLLRY-NH2
Certificate of Analysis
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Product Specific Notices for FSLLRY-NH2
For research use only
Citations for FSLLRY-NH2
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Species: HumanAssay Type: In VitroCell Line/Tissue: endothelial cellVerified Customer | Posted 07/25/2023F3LLRY-NH2 was used to test its effect on positive control-induced migration.
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