Galloflavin

Tocris Bioscience | Catalog # 4795

Lactate dehydrogenase inhibitor; impairs aerobic glycolysis
Tocris Bioscience
Discontinued Product
4795 has been discontinued. View all Lactate Dehydrogenase A/LDHA Inhibitors products.

Key Product Details

Description

Lactate dehydrogenase inhibitor; impairs aerobic glycolysis
View all Lactate Dehydrogenase A/LDHA Inhibitors »

Product Description

Galloflavin is an inhibitor of human lactate dehydrogenase (LDH) (Ki values are 5.46 and 15.1 μM for LDH-A and LDH-B, respectively, in competition with pyruvate). Inhibits lactate production and decreases ATP synthesis in PLD/PRF/5 cells; thought to decrease cell viability via impairment of aerobic glycolysis.

Product Specifications for Galloflavin

Molecular Weight

316.26

Formula

C12H5O8K

Storage

Store at -20°C

Purity

≥95% (HPLC)

Chemical Name

3,8,9,10-Tetrahydroxypyrano[3,2-c][2]benzopyran-2,6-dione potassium salt

CAS Number

1780260-20-9

PubChem ID

90488971

InChI Key

XSPGPNGPTLAWMC-UHFFFAOYSA-M

SMILES

[K+].OC1=C(O)C(O)=C2C3=C(OC(=O)C2=C1)C=C([O-])C(=O)O3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 1.58 5

Preparing Stock Solutions for Galloflavin

The following data is based on the product molecular weight 316.26.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.05 mM 63.24 mL 316.20 mL 632.39 mL
0.25 mM 12.65 mL 63.24 mL 126.48 mL
0.5 mM 6.32 mL 31.62 mL 63.24 mL
2.5 mM 1.26 mL 6.32 mL 12.65 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 14 publications citing the usage of this product.

Product Documents for Galloflavin

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Galloflavin

For research use only

Customer Reviews for Galloflavin (1)

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  • We got expected effect on cells
    Name: Anonymous
    Species: Mouse
    Assay Type: In Vitro
    Cell Line/Tissue: Primary pancreatic ductal epithelial cells
    Verified Customer | Posted 04/03/2020
    20 μM galloflavin
    Galloflavin 4795

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