GAT3 Antibody - BSA Free

Novus Biologicals | Catalog # NBP2-84955

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Format

BSA Free
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Product Specifications

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human GAT3. Peptide sequence: EGTLPEKLQKLTTPSTDLKMRGKLGVSPRMVTVNDCDAKLKSDGTIAAIT The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Scientific Data Images for GAT3 Antibody - BSA Free

Western Blot: GAT3 Antibody [NBP2-84955]

Western Blot: GAT3 Antibody [NBP2-84955]

Western Blot: GAT3 Antibody [NBP2-84955] - Host: Rabbit. Target Name: SLC6A11. Sample Type: PANC1 Whole Cell lysates. Antibody Dilution: 1.0ug/ml

Applications for GAT3 Antibody - BSA Free

Application
Recommended Usage

Western Blot

1.0 ug/ml

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Format

BSA Free

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: GAT3

Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl negative channel associated with the GABAA receptor (GABAA-R) subtype. GABA plasma membrane transporters (GATs) influence synaptic neurotransmission by high-affinity uptake and release of GABA. To date, four distinct GABA transporters have been identified: GAT-1, GAT-2, GAT-3, and BGT-1. GAT-3 has been found to be localized to astrocytes within the cerebral cortex indicating that this transporter mediates GABA uptake into glial cells (Minelli et al., 1996).

Long Name

Sodium- and chloride-dependent GABA transporter 3

Alternate Names

GABT3, GAT-3, SLC6A11

Gene Symbol

SLC6A11

Additional GAT3 Products

Product Documents for GAT3 Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for GAT3 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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