GBR 13069 dihydrochloride

Key Product Details

Product Description

GBR 13069 dihydrochloride is a potent inhibitor of dopamine uptake (IC₅₀ = 40 nM). Centrally active following systemic administration in vivo.

Product Specifications for GBR 13069 dihydrochloride

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for GBR 13069 dihydrochloride

The following data is based on the product molecular weight 521.48.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.05 mM	38.35 mL	191.76 mL	383.52 mL
0.25 mM	7.67 mL	38.35 mL	76.70 mL
0.5 mM	3.84 mL	19.18 mL	38.35 mL
2.5 mM	0.77 mL	3.84 mL	7.67 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Mayer Prevention of the nigrostriatal toxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine by inhibitors of 3,4-dihydroxyphenylethylamine transport. J.Neurochem. 1986 PMID: 3489072
• Van der Zee and Hespe Interaction between substituted 1-[2-diphenylmethoxyethyl]piperazines and DA receptors. Neuropharmacology 1985 PMID: 4094653
• Heikkila Behavioural properties of GBR12909, GBR13069 and GBR13098: specific inhibitors of DA uptake. Eur.J.Pharmacol. 1984 PMID: 6237922

Product Documents for GBR 13069 dihydrochloride