GC 1

Tocris Bioscience | Catalog # TB4554-RMU

GC1 synthesized to Ancillary Material Grade
Tocris Bioscience
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Key Product Details

Description

GC1 synthesized to Ancillary Material Grade
View all Ancillary Material Grade Compounds »

Product Description

GC 1 is a thyromimetic; high affinity agonist at thyroid hormone receptor (TR) β and TRα receptors (KD values are 67 and 440 pM respectively). Displays 5- and 100-fold greater potency than the endogenous agonist T3 in vitro at TRα1 and TRβ1 receptors respectively. Promotes reverse cholesterol transport in chow- and fat-fed mice. Induces proliferation of hepatocytes and pancreatic acinar cells in rats independent of prior tissue injury.

This product is Bio-Techne's ancillary Material Grade version of GC 1 (Cat. No. 4554). Suitable for use in research and further manufacturing of cell therapies. Find out more about our Ancillary Material Grade product range.

Product Specifications for GC 1

Formula

C20H24O4

Storage

Store at -20°C (± 5°C)

Purity

≥98%

Chemical Name

2-[4-[[4-Hydroxy-3-(1-methylethyl)phenyl]methyl]-3,5-dimethylphenoxy]acetic acid

CAS Number

211110-63-3

PubChem ID

9862248

InChI Key

QNAZTOHXCZPOSA-UHFFFAOYSA-N

SMILES

CC1=CC(OCC(O)=O)=CC(C)=C1CC2=CC(C(C)C)=C(O)C=C2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

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Background References

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Product Documents for GC 1

Certificate of Analysis

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Product Specific Notices for GC 1

For research use only

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