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Ginkgolic Acid

Catalog #: 6326
1 Citation Datasheet / COA / SDS

Discontinued Product

6326 has been discontinued.
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Ginkgolic Acid | CAS No. 22910-60-7 | Additional Ligase Inhibitors
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Description: Inhibits SUMOylation by binding E1

Chemical Name: 2-Hydroxy-6-(8Z)-8-pentadecenylbenzoic acid

Purity: ≥97%

Product Details
Citations (1)
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Biological Activity

Ginkgolic Acid is an inhibitor of SUMOylation (IC50 = 3 μM). Directly binds E1 and inhibits formation of E1-SUMO intermediate. Protects against amyloid β-induced impairment of neurotransmission and synaptic plasticity. Also suppresses CD44 and MMP14 expression in breast cancer cells, eliminating cancer stem cells and inhibiting tumorigenesis.

Technical Data

M.Wt:
346.5
Formula:
C22H34O3
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Purity:
≥97%
Storage:
Store at -20°C
CAS No:
22910-60-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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Citation for Ginkgolic Acid

The citations listed below are publications that use Tocris products. Selected citations for Ginkgolic Acid include:

1 Citation: Showing 1 - 1

  1. Pharmacological targeting of Sam68 functions in colorectal cancer stem cells.
    Authors: Yannick D Et al.
    iScience  2021;24:103442

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