Ginkgolide B

Tocris Bioscience | Catalog # 1657

PAF receptor antagonist
Tocris Bioscience
Discontinued Product
1657 has been discontinued. View all Platelet-activating Factor Receptor Antagonists products.

Key Product Details

Description

PAF receptor antagonist

Alternative Names

BN 52021
View all Platelet-activating Factor Receptor Antagonists »

Product Description

Ginkgolide B is a platelet-activating factor (PAF) receptor antagonist (Ki = 1.3 μM). Inhibits neutrophil degranulation and superoxide production in vitro and inhibits bronchoconstriction and is neuroprotective following oral administration in vivo.

Product Specifications for Ginkgolide B

Molecular Weight

424.40

Formula

C20H24O10

Storage

Desiccate at +4°C

Chemical Name

(1R,3S,3aS,4R,6aR,7aR,7bR,8S,10aS,11R,11aR)-3-(1,1-Dimethylethyl)hexahydro-4,7b,11-trihydroxy-8-methyl-9H-1,7a-(epoxymethano)-1H,6aH-cyclopenta[c]furo[2,3-b]furo[3',2':3,4]cyclopenta[1,2-d]furan-5,9,12(4H)-trione

CAS Number

15291-77-7

PubChem ID

10971931

InChI Key

SQOJOAFXDQDRGF-OTJOYSMWSA-N

SMILES

O=C1[C@@H](C)[C@@]2(O)[C@@]([C@H](O)C34[C@]52O[C@@]6([H])[C@]([C@@H](O)C(O6)=O)3[C@H]([C@](C)(C)C)C[C@H]4O[C@]5=O)([H])O1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 42.44 100
Ethanol 10.61 25

Preparing Stock Solutions for Ginkgolide B

The following data is based on the product molecular weight 424.40.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.36 mL 11.78 mL 23.56 mL
5 mM 0.47 mL 2.36 mL 4.71 mL
10 mM 0.24 mL 1.18 mL 2.36 mL
50 mM 0.05 mL 0.24 mL 0.47 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 9 publications citing the usage of this product.

Product Documents for Ginkgolide B

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Ginkgolide B

For research use only

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