GLYX 13
Tocris Bioscience | Catalog # 3406
Key Product Details
Description
Alternative Names
Product Description
GLYX 13 is a NMDA receptor partial agonist that acts at the glycine site. Simultaneously acts as a promoter of the induction of long-term potentiation (LTP) and as a suppressor of long-term depression (LTD). Also promotes VGF and BDNF release and increases ERK/mTOR signaling. Exhibits nootropic, neuroprotective and antinociceptive activity, and enhances learning, memory and cognition in vivo. Brain penetrant.
Product Specifications for GLYX 13
Molecular Weight
Formula
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Purity
CAS Number
PubChem ID
InChI Key
SMILES
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solubility | Soluble to 2mg/ml in water |
Calculators
Background References
References are publications that support the biological activity of the product. See our Citations tab to view 10 publications citing the usage of this product.
- Shen ERK/mTOR signaling may underlying the antidepressant actions of rapastinel in mice. Transl.Psychiatry 2022 PMID: 36550125
- Wood Antinociceptive action of GLYX-13: a N-MthD.-aspartate receptor glycine site partial agonist. Neuroreport. 2008 PMID: 18580579
- Burgdorf The N-MthD.-aspartate receptor modulator GLYX-13 enhances learning and memory, in young adult and learning impaired aging rats. Neurobiol.Aging 2009 PMID: 19446371
- Moskal GLYX-13: A monoclonal antibody-derived peptide that acts as an N-MthD.-aspartate receptor modulator. Neuropharmacology 2005 PMID: 16051282
Product Documents for GLYX 13
Certificate of Analysis
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Product Specific Notices for GLYX 13
For research use only
Related Research Areas
Citations for GLYX 13
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