GP 2a

Key Product Details

Product Description

GP 2a is a selective CB₂ receptor agonist; K_i values are 7.6 and 900 nM for CB₂ and CB₁ receptors respectively. Increases P-ERK1/2 expression in HL-60 cells in vitro.

Product Specifications for GP 2a

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for GP 2a

The following data is based on the product molecular weight 440.36.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.5 mM	4.54 mL	22.71 mL	45.42 mL
2.5 mM	0.91 mL	4.54 mL	9.08 mL
5 mM	0.45 mL	2.27 mL	4.54 mL
25 mM	0.09 mL	0.45 mL	0.91 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Murineddu Tricyclic pyrazoles. 4. Synthesis and biological evaluation of analogues of the robust and selective CB2 cannabinoid ligand 1-(2',4'-dichlorophenyl)-6-methyl-N-piperidin-1-yl-1,4-dihydroindeno[1,2-c]pyrazole-3-carboxam J.Med.Chem. 2006 PMID: 17149879

Product Documents for GP 2a