Histone H4 [Dimethyl Lys20] Antibody Blocking Peptide

Novus Biologicals | Catalog # NB21-2089PEP

Novus Biologicals
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Key Product Details

Applications

Antibody Competition
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Product Specifications

Description

A HIST4H4 antibody blocking peptide.

Modification

Dimethyl Lys20

Application Notes

This peptide is useful as a blocking peptide for NB21-2089. For further blocking peptide related protocol, click here.

Specificity

This peptide is specific for NB21-2089 only.

Protein / Peptide Type

Antibody Blocking Peptide

Scientific Data Images for Histone H4 [Dimethyl Lys20] Antibody Blocking Peptide

Formulation, Preparation, and Storage

NB21-2089PEP
Formulation Lyophilized. Reconstitute in 40 ul of diH20.
Preservative No Preservative
Concentration Lyoph
Shipping The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at -80C. Avoid freeze-thaw cycles.

Background: Histone H4

Histone proteins H3, H4, H2A, and H2B function as building blocks to package eukaryotic DNA into repeating nucleosome units that are folded in higher order chromatin fibers. The nucleosome is composed of an octamer containing a H3/H4 tetramer and two H2A/H2B dimers, surrounded by approximately 146 base pairs of DNA. A diverse and elaborate array of post-translational modifications including acetylation, phosphorylation, methylation, ubiquitination, and ADP-ribosylation occurs on the N-terminal tail domains of histones. Methylation of position-specific lysine residues in histone N termini is a central modification for regulating epigenetic transitions in chromatin. Each methylatable lysine residue can exist in a mono, di, or tri methylated state. Arginine resdiues can also by mono or di methylated.

Alternate Names

H4, H4/M, H4FM, H4M, HIST1H4I, HIST4H4, Histone Cluster 1 H4, Histone Cluster 1 H4i, Histone Cluster 4 H4

Gene Symbol

H4C16

Additional Histone H4 Products

Product Documents for Histone H4 [Dimethyl Lys20] Antibody Blocking Peptide

Certificate of Analysis

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Product Specific Notices for Histone H4 [Dimethyl Lys20] Antibody Blocking Peptide

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

Related Research Areas

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Associated Pathways

Notch Signaling Pathways Notch Signaling Pathway Thumbnail