HJC 0350

Key Product Details

Product Description

HJC 0350 is a selective Epac2 inhibitor (IC₅₀ = 0.3 μM). Displays no effect on Epac1. Blocks stimulation of the Epac2-FL FRET sensor in HEK293 cells.

Product Specifications for HJC 0350

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for HJC 0350

The following data is based on the product molecular weight 277.38.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.5 mM	7.21 mL	36.05 mL	72.10 mL
2.5 mM	1.44 mL	7.21 mL	14.42 mL
5 mM	0.72 mL	3.61 mL	7.21 mL
25 mM	0.14 mL	0.72 mL	1.44 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 15 publications citing the usage of this product.

• Chen Identification and characterization of small molecules as potent and specific EPAC2 antagonists. J.Med.Chem. 2013 PMID: 23286832

Product Documents for HJC 0350