HP1 alpha Antibody

Novus Biologicals | Catalog # NBP3-18650

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit
View all HP1 alpha Primary Antibodies »

Product Specifications

Immunogen

Polyclonal antibody raised in rabbit against human HP1 alpha (Heterochromatin protein 1 homolog alpha), using the full length recombinant GST tagged protein.

Clonality

Polyclonal

Host

Rabbit

Scientific Data Images for HP1 alpha Antibody

Western Blot: HP1 alpha Antibody [NBP3-18650]

Western Blot: HP1 alpha Antibody [NBP3-18650]

Western Blot: HP1 alpha Antibody [NBP3-18650] - Figure 1. Western blot analysis using the antibody against hHP1 alpha Western blot was performed on nuclear extracts from HeLa cells (HeLa NE, 20 ug) using the antibody against hHP1 alpha diluted 1:1,000 in TBS-Tween containing 5% skimmed milk. A molecular weight marker (in kDa) is shown on the left. The location of the three HP1 isoforms of interest is indicated on the right, demonstrating that the antibody only recognizes the alpha isoform.

Applications for HP1 alpha Antibody

Application
Recommended Usage

Western Blot

1:1000

Formulation, Preparation, and Storage

Purification

Whole Antiserum

Formulation

Whole antiserum

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C short term. Aliquot and store at -80C long term. Avoid freeze-thaw cycles.

Background: HP1 alpha

Heterochromatin protein-1 (HP1) is a methyl-lysine binding adapter protein that is involved in a variety important functions in the cell nucleus. Localized at heterochromatin sites, HP1 is responsible for gene repression by heterochromatin formation, transcriptional activation, regulation of binding of cohesion complexes to centromere, sequesteration of genes to nuclear periphery, transcriptional arrest, maintenance of heterochromatin integrity, gene repression at single nucleosome level and gene repression by heterochromatization of euchromatin.

HP1 antibodies are useful tools for research on transcription regulation and epigenetic signaling.

Alternate Names

Antigen p25, chromobox homolog 5, chromobox homolog 5 (Drosophila HP1 alpha), chromobox homolog 5 (HP1 alpha homolog, Drosophila), chromobox protein homolog 5, Heterochromatin protein 1 homolog alpha, heterochromatin protein 1-alpha, HP1, HP1 alpha, HP1 alpha homolog, HP1A, HP1-ALPHA, HP1Hs alpha, HP1Hs-alpha

Gene Symbol

CBX5

UniProt

P45973 (Human)

Additional HP1 alpha Products

Product Documents for HP1 alpha Antibody

Certificate of Analysis

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Product Specific Notices for HP1 alpha Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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