Human Apolipoprotein A-II/ApoA2 Alexa Fluor® 750-conjugated Antibody

Catalog #: FAB4215S Datasheet / COA / SDS

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FAB4215S-100UG

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Human Apolipoprotein A-II/ApoA2 Alexa Fluor® 750-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human ApoA2 in direct ELISAs and Western blots. Does not cross‑react with recombinant human (rh) ApoA1 or rhApoE.

Source

Monoclonal Rat IgG2a Clone # 395906

Purification

Protein A or G purified

Immunogen

E. coli-derived recombinant human ApoA2
Gln24-Gln100
Accession # P02652

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 750 (Excitation= 749 nm, Emission= 775 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: Apolipoprotein A-II/ApoA2

Apolipoprotein A2 (ApoA2) is a major protein component of serum HDL. It is produced by the liver and is involved in cholesteryl ester formation and cholesterol transport from tissues to the liver. Polymorphisms of ApoA2 are associated with disorders of cholesterol and fatty acid metabolism. ApoA2 can form disulfide-linked 17 kDa homodimers and heterodimers with other apolipoproteins. Mature human ApoA2 shares 96% aa sequence identity with chimpanzee ApoA2 and 48% - 66% aa sequence identity with bovine, equine, mouse, and rat ApoA2.

Entrez Gene IDs

336 (Human); 11807 (Mouse); 25649 (Rat)

Alternate Names

Alp-2; APOA2; apoAII; Apo-AII; ApoA-II; Apolipoprotein A2; Apolipoprotein AII; Apolipoprotein A-II; Hdl-1