Human ETV1 Alexa Fluor® 594-conjugated Antibody

Catalog #: FAB9389T Datasheet / COA / SDS

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FAB9389T-100UG

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Human ETV1 Alexa Fluor® 594-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human ETV1 in direct ELISAs and Western blots.

Source

Monoclonal Mouse IgG1 Clone # 815207

Purification

Protein A or G purified

Immunogen

E. coli-derived recombinant human ETV1
Asn120-Leu190
Accession # P50549

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 594 (Excitation= 590 nm, Emission= 617 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: ETV1

ETS translocation variant 1 is a protein that in humans is encoded by the ETV1 gene. ETV-1, ETV-4 and ETV-5 proteins form the PEA3 subfamily of ETS transcription factors. Posttranslational modifications in this subfamily promote cell proliferation, motility and invasion. Disregulation of ETV-1 has been observed in gastrointestinal stromal and protatic tumors, and in triple-negative breast cancer. Human ETV-1 is a 477 aminoacids (aa) protein with at least six known isoforms. Over the immunogen used in this antibody (aa120-190), ETV-1 sequences are 96% identical to mouse and rat ETV-1 sequences.

Long Name

ETS Translocation Variant 1

Entrez Gene IDs

2115 (Human); 14009 (Mouse); 362733 (Rat)

Alternate Names

DKFZp781L0674; ER81; ER81ets variant gene 1; ETS translocation variant 1; ets variant 1; Ets-related protein 81; ETV1; MGC104699; MGC120533; MGC120534