Human gamma-Glutamylcyclotransferase/CRF21 Alexa Fluor® 488-conjugated Antibody

Catalog #: AF5086G Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
AF5086G-100UG

Save 15% on Select RUO Reagents. See Details.

All gamma-Glutamylcyclotransferase/CRF21 Antibodies

Product Details

Supplemental Products

Reviews

Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human gamma-Glutamylcyclotransferase/CRF21 Alexa Fluor® 488-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human gamma ‑Glutamylcyclotransferase/CRF21 in Western blots.

Source

Polyclonal Sheep IgG

Purification

Antigen Affinity-purified

Immunogen

E. coli-derived recombinant human Î³â€‘Glutamylcyclotransferase/CRF21
Met1-Leu188
Accession # O75223

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 488 (Excitation= 488 nm, Emission= 515-545 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: gamma-Glutamylcyclotransferase/CRF21

Gamma-glutamylcyclotransferase (GGCT; also Cytochrome c-releasing factor 21, CRF21, C7orf24 or LOC79017) is a 21 kDa AIG2-like family member. It is a cytosolic protein that induces the release of Cytochrome c from mitochondria, possibly initiating apoptosis. Human CRF21 is 188 amino acids (aa) in length and is a complex of beta -sheets and alpha -helices that create two terminal domains. It has been proposed that CRF21 forms homodimers. There are at least two possible splice variants of human CRF21, one showing a 70 aa substitution, while the second variant shows an 18 aa substitution for aa 97‑188. Full-length human CRF21 is 82% aa identical to mouse CRF21.

Long Name

Cytochrome c Releasing Factor 21

Entrez Gene IDs

79017 (Human); 110175 (Mouse); 685702 (Rat)

Alternate Names

C7orf24; CRF21; gammaGlutamylcyclotransferase; gamma-Glutamylcyclotransferase; GCTG; GGC; GGCT; LOC79017; MGC3077