Human GFR alpha-4/GDNF R alpha-4 Alexa Fluor® 488-conjugated Antibody

Catalog #: FAB1439G Datasheet / COA / SDS

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FAB1439G-100UG

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All GFR alpha-4/GDNF R alpha-4 Antibodies

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human GFR alpha-4/GDNF R alpha-4 Alexa Fluor® 488-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human GFR alpha ‑4/GDNF R alpha ‑4 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human (rh) GFR alpha -1, recombinant rat GFR alpha -1, rhGFR alpha -2, rhGFR alpha -3, or recombinant mouse GFR alpha -4 is observed.

Source

Monoclonal Mouse IgG1 Clone # 215725

Purification

Protein A or G purified

Immunogen

Mouse myeloma cell line NS0-derived recombinant human GFRÎ±â€‘4/GDNF RÎ±â€‘4
Asn24-Ser245 (Ser140Cys)(predicted)
Accession # NP_071422

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 488 (Excitation= 488 nm, Emission= 515-545 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: GFR alpha-4/GDNF R alpha-4

GFR alpha -4 is a member of a family of at least four cysteine-rich GPI-linked cell surface proteins that function as ligand binding subunits for the GDNF family (GDNF, neurturin, persephin and artemin). A functional receptor complex is achieved through association with the c-Ret receptor tyrosine kinase. GFR alpha -4 preferentially binds persephin.

Long Name

Glial Cell line-derived Neurotrophic Factor Receptor alpha 4

Entrez Gene IDs

64096 (Human); 14588 (Mouse)

Alternate Names

GDNF family receptor alpha 4; GDNF family receptor alpha-4; GDNF R alpha-4; GDNF receptor alpha-4; GDNFR-alpha-4; GFR alpha4; GFR alpha-4; GFR receptor alpha 4; GFRA4; GFRa-4; GFR-alpha-4; Persephin receptor