Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Western Blot

Cited:

Western Blot, Flow Cytometry

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 86911
View all ICAM-2/CD102 Primary Antibodies »

Product Specifications

Immunogen

S. frugiperda insect ovarian cell line Sf 21-derived recombinant human ICAM‑2/CD102
Lys25-Gln223 (predicted)
Accession # CAA33630

Specificity

Detects human ICAM‑2/CD102 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human (rh) CEACAM-1, recombinant mouse (rm) DCC, rhICAM-1, rmICAM-2, rhICAM-3, rmICAM-5, rmMAdCAM-1, rhCD31, or rmVCAM-1 is observed.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications for Human ICAM‑2/CD102 Antibody

Application
Recommended Usage

Western Blot

1 µg/mL
Sample: Recombinant Human ICAM‑2/CD102 Fc Chimera (Catalog # 803-I2)

Formulation, Preparation, and Storage

Purification

Protein A or G purified from ascites

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: ICAM-2/CD102

Intercellular Adhesion Molecule-2 (ICAM-2, CD102), a member of the immunoglobulin superfamily, binds the leukocyte integrins LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). ICAM-2 is constitutively expressed at high levels on vascular endothelial cells and lymphohematopoietic cells. ICAM-2 mediated adhesion has been shown to provide a co-stimulatory signal for T cell aggregation, NK cytotoxicity and NK cell migration.

References

  1. Somersalo, K. et al. (1995) J. Biol. Chem. 270:8629.
  2. Hayflick, J. et al. (1998) Immunologic Res. 17:313.

Long Name

Intercellular Adhesion Molecule 2

Alternate Names

CD102, ICAM2

Entrez Gene IDs

3384 (Human); 15896 (Mouse)

Gene Symbol

ICAM2

UniProt

CAA33630

Additional ICAM-2/CD102 Products

Product Documents for Human ICAM‑2/CD102 Antibody

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

Download SDS

Product Specific Notices for Human ICAM‑2/CD102 Antibody

For research use only

Citations for Human ICAM‑2/CD102 Antibody

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