Human IFN-alpha I Alexa Fluor® 750-conjugated Antibody

Catalog #: FAB100801S Datasheet / COA / SDS

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FAB100801S-100UG

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All IFN-alpha I Antibodies

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Human IFN-alpha I Alexa Fluor® 750-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human IFN‑ alpha I in direct ELISAs.

Source

Monoclonal Mouse IgG1 Clone # 995819

Purification

Protein A or G purified

Immunogen

Human embryonic kidney cell line HEK293-derived recombinant human IFNâ€‘Î±I
Met1-Asp189
Accession # P01571

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 750 (Excitation= 749 nm, Emission= 775 nm)

Applications

Recommended Concentration

Sample

Neutralization

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: IFN-alpha I

Interferon-alpha (IFN-alpha, IFNA), also known as leukocyte interferon, represents a group of related but distinct proteins that share over 95% amino acid sequence homology. They are members of the type I interferon family which share a common cell surface receptor composed of two subunits, a 100 kDa ligand-binding subunit (IFN-alpha R2) and a 125 kDa ligand binding and signal transduction subunit (IFN-alpha R1) that is involved both in ligand binding and signal transduction. There are at least 18 different IFNA subtypes, and the major subtypes identified are IFNA1, IFNA2, IFNA8, IFNA10, IFNA14 and IFNA21.

Long Name

Interferon alpha I

Entrez Gene IDs

3451 (Human)

Alternate Names

IFNA; IFNA17; IFNalpha I; IFN-alpha I; IFN-alpha-17; IFN-alphaI; INFA; interferon alpha-17; Interferon alpha-88; Interferon alpha-I'; Interferon alpha-T; interferon alpha-WA; interferon, alpha 17; LeIF I; LEIF2C1