Interleukin 34 (IL-34) is secreted as a homodimer consisting of 39 kDa monomers. It belongs to no known cytokine family. The mature chain contains one potential site for N-linked glycosylation. IL-34 is widely expressed, but it is most abundant in the spleen. The receptor for IL-34 is colony-stimulating factor 1 receptor (CSF‑1R). Functionally, IL-34 stimulates monocyte viability.
Key Product Details
Species Reactivity
Human
Applications
ELISA Capture (Matched Antibody Pair)
Label
Unconjugated
Antibody Source
Monoclonal Mouse IgG1 Clone # 578410
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Product Specifications
Immunogen
Mouse myeloma cell line NS0-derived recombinant human IL-34
Asn21-Pro242
Accession # Q6ZMJ4
Asn21-Pro242
Accession # Q6ZMJ4
Specificity
Detects human IL-34 in sandwich immunoassays. In this format, no cross-reactivity with recombinant mouse IL-34 is observed.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG1
Applications for Human IL‑34 Antibody
Human IL-34 Sandwich Immunoassay
Please Note: Optimal dilutions of this antibody should be experimentally determined.
Reviewed Applications
Read 1 review rated 2 using MAB52651 in the following applications:
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.
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Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Calculators
Background: IL-34
Long Name
Interleukin 34
Alternate Names
C16orf77, IL34
Gene Symbol
IL34
UniProt
Additional IL-34 Products
Product Documents for Human IL‑34 Antibody
Product Specific Notices for Human IL‑34 Antibody
For research use only
Related Research Areas
Customer Reviews for Human IL‑34 Antibody (1)
2 out of 5
1 Customer Rating
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Application: MicroarraySample Tested: EDTA PlasmaSpecies: HumanVerified Customer | Posted 12/06/2019Antibody was printed on custom arrays and incubated with fluorescently labeled human EDTA plasma
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