Human Lipocalin‑1 Alexa Fluor™ Plus 488‑conjugated Antibody

R&D Systems | Catalog # AF1708AFP488

R&D Systems

Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Alexa Fluor Plus 488 (Excitation = 493 nm, Emission = 518 nm)

Antibody Source

Polyclonal Goat IgG
View all Lipocalin-1 Primary Antibodies »

Product Specifications

Specificity

Detects human Lipocalin-1 in direct ELISAs and Western blots. In these formats, less than 5% cross‑reactivity with recombinant human Lipocalin-2 is observed.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for Human Lipocalin‑1 Alexa Fluor™ Plus 488‑conjugated Antibody

Application
Recommended Usage

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Formulation

Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: Lipocalin-1

Lipocalin-1, also known as tear prealbumin or von Ebner’s gland protein (VEGP), is encoded by the LCN1 gene (1 - 3). It is a member of the Lipocalin superfamily that binds many different classes of lipophylic chemicals (4). Lipocalin-1 contains three sequence motifs similar to the cystatins, a superfamily of cysteine protease inhibitors (5). In fact, it has been suggested that Lipocalin-1 is a physiological inhibitor of cysteine proteases and plays a role in the control of inflammatory processes in oral and ocular tissues (5). rhLipocalin-1 corresponds to the mature and secreted protein. It is a weak inhibitor of cysteine proteases such as cathepsin V, which is similar to rhCystatin S (R&D Systems, Catalog # 1296-PI).

References

  1. Redl, B. et al. (1992) J. Biol. Chem. 267:20282.
  2. Blaker, M. et al. (1993) Biochim. Biophys. Acta 1172:131.
  3. Lassagne, H. and A.M. Gachon (1993) Exp. Eye Res. 56:605.
  4. Redl, B. et al. (2000) Biochim. Biophys. Acta 1482:241.
  5. van’t Hof, W. et al. (1997) J. Biol. Chem. 272:1837.

Alternate Names

LCN1, Lipocalin1, Tear Prealbumin, VEGP

Entrez Gene IDs

3933 (Human)

Gene Symbol

LCN1

UniProt

P31025

Additional Lipocalin-1 Products

Product Documents for Human Lipocalin‑1 Alexa Fluor™ Plus 488‑conjugated Antibody

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Human Lipocalin‑1 Alexa Fluor™ Plus 488‑conjugated Antibody


This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com.

For research use only

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