Human MALT1 Alexa Fluor® 488-conjugated Antibody

Catalog #: FAB4850G Datasheet / COA / SDS

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FAB4850G-100UG

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Human MALT1 Alexa Fluor® 488-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human MALT1 in Western blots.

Source

Monoclonal Mouse IgG1 Clone # MALT1-C

Purification

Protein A or G purified

Immunogen

Recombinant human MALT1
Asp701-Thr808
Accession # Q9UDY8

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 488 (Excitation= 488 nm, Emission= 515-545 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: MALT1

Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1) is an approximately 91 kDa intracellular adaptor protein that forms a complex with Bcl10 and CARMA-1. The caspase-like domain of MALT1 cleaves Bcl10 and the NF kappa B inhibitor A20. This results in NF kappa B activation following signal transduction from cell surface ITAM-containing receptors including the T cell and B cell antigen receptors. Human MALT1 shares 87% aa sequence identity with mouse and rat MALT1.

Long Name

Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1

Entrez Gene IDs

10892 (Human); 240354 (Mouse); 307366 (Rat)

Alternate Names

caspase-like protein; DKFZp434L132; EC 3.4.22.-; MALT associated translocation; MALT lymphoma-associated translocation; MALT1; MLT1; MLTMALT-lymphoma associated translocation; mucosa associated lymphoid tissue lymphoma translocation gene 1; mucosa-associated lymphoid tissue lymphoma translocation protein 1; Paracaspase