Human Marapsin/Pancreasin Alexa Fluor® 700-conjugated Antibody

Catalog #: FAB1988N Datasheet / COA / SDS

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FAB1988N-100UG

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Human Marapsin/Pancreasin Alexa Fluor® 700-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human Marapsin/Pancreasin in direct ELISAs and Western blots. Reacts with an epitope within the mature chain. In direct ELISAs and Western blots, no cross-reactivity with recombinant mouse Marapsin is observed.

Source

Monoclonal Mouse IgG1 Clone # 243305

Purification

Protein A or G purified

Immunogen

Mouse myeloma cell line NS0-derived recombinant human Marapsin/Pancreasin
Ala23-Lys290
Accession # Q9BQR3

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 700 (Excitation= 675-700 nm, Emission= 723 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Immunoprecipitation

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: Marapsin/Pancreasin

Marapsin, pancreasin, and channel-activating protease 2 (CAP-2) are different names for the same serine protease that is expressed strongly in the pancreas (1, 2). The protein is synthesized with a signal peptide (amino acids 1‑22), a pro peptide (aa 23‑34) and a mature chain (aa 35‑290) corresponding to the serine protease domain.

Entrez Gene IDs

83886 (Human); 213171 (Mouse)

Alternate Names

CAP-2; CAPH2; channel-activating protease 2; EC 3.4.21; EC 3.4.21.-; EC 3.4.21.4; EC 3.4.21.43; Marapsin; MPN; MPNMarapsin; Pancreasin; protease, serine 27; PRSS27; serine protease 27