Human/Mouse DDX5 Alexa Fluor® 350-conjugated Antibody

Catalog #: FAB6370U Datasheet / COA / SDS

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FAB6370U-100UG

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All DDX5 Antibodies

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human/Mouse DDX5 Alexa Fluor® 350-conjugated Antibody Summary

Species Reactivity

Human, Mouse

Specificity

Detects human and mouse DDX5 in Western blots.

Source

Monoclonal Mouse IgG2a Clone # 632813

Purification

Protein A or G purified

Immunogen

E. coli-derived recombinant human DDX5
Asn448-Gln614
Accession # P17844

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 350 (Excitation= 346 nm, Emission= 442 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: DDX5

DDX5, also known as p68 RNA helicase, is a 614 amino acid (aa), 68 kDa member of the DEAD box family of RNA helicases that contain the conserved Asp‑Glu‑Ala‑Asp (DEAD) motif. DDX5 influences RNA transport, transcription, ribosome assembly, spliceosome function, RNA degradation, and the initiation of translation. DDX5 shares 87% aa identity with DDX17 within the central region and the two are often expressed together. The C-terminal region used as an immunogen shares 96% and 99% aa identity with mouse and rat DDX5, respectively, but lies mainly outside the DDX17 homology region.

Long Name

DEAD Box Protein 5

Entrez Gene IDs

1655 (Human); 13207 (Mouse); 287765 (Rat)

Alternate Names

B-cell CLL/lymphoma 7 protein family member C; B-cell CLL/lymphoma 7C; DDX5; DEAD/H; G17P1; HELR; HLR1; HUMP68