Osteocrin Antibody (311417)

R&D Systems | Catalog # MAB2620

R&D Systems

Key Product Details

Species Reactivity

Validated:

Human, Mouse

Cited:

Mouse

Applications

Validated:

Western Blot, Immunoprecipitation

Cited:

ELISA Capture

Label

Unconjugated

Antibody Source

Monoclonal Rat IgG2A Clone # 311417
View all Osteocrin Primary Antibodies »

Product Specifications

Immunogen

E. coli-derived recombinant mouse Osteocrin
Val28-Gly130
Accession # P61364

Specificity

Detects human and mouse Osteocrin in direct ELISAs and Western blots.

Clonality

Monoclonal

Host

Rat

Isotype

IgG2A

Applications for Osteocrin Antibody (311417)

Application
Recommended Usage

Immunoprecipitation

25 µg/mL
Sample: Conditioned cell culture medium spiked with Recombinant Human or Recombinant Mouse Osteocrin, see our available Western blot detection antibodies

Western Blot

1 µg/mL
Sample: Recombinant Mouse Osteocrin

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: Osteocrin

Mouse Osteocrin, also known as Musclin, is a secreted protein that is primarily expressed in bone and muscle. It is synthesized as an 11 kDa proprotein that undergoes proteolytic processing to generate a mature 50 amino acid (5 kDa) C-terminal active peptide. It was found to modulate osteoblast differentation and to regulate glucose metabolism in muscles. Mouse Osteocrin proprotein shares 77% and 78% amino acid sequence identity with the rat and human protein, respectively.

Alternate Names

Musclin, OSTN

Entrez Gene IDs

344901 (Human); 239790 (Mouse)

Gene Symbol

OSTN

UniProt

P61364

Additional Osteocrin Products

Product Documents for Osteocrin Antibody (311417)

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

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Product Specific Notices for Osteocrin Antibody (311417)

For research use only

Citations for Osteocrin Antibody (311417)

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