Axin-1 Antibody [Alexa Fluor™ Plus 488]

R&D Systems | Catalog # AF3287AFP488

R&D Systems

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot

Label

Alexa Fluor Plus 488 (Excitation = 493 nm, Emission = 518 nm)

Antibody Source

Polyclonal Goat IgG
View all Axin-1 Primary Antibodies »

Product Specifications

Immunogen

E. coli-derived recombinant human Axin-1

Specificity

Detects human, mouse and rat Axin-1 in Western blots.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for Axin-1 Antibody [Alexa Fluor™ Plus 488]

Application
Recommended Usage

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Formulation

Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: Axin-1

Axin-1 is a negative regulator of the Wnt signaling pathway, which is involved in regulation of embryonic axis formation in vertebrates. Axin-1 binds to beta -catenin and glycogen synthase kinase-3 (GSK-3) to promote beta -catenin phosphorylation and subsequent degradation. Axin-1 also binds to the adenomatous polyposis coli (APC) gene, a known tumor suppressor that also regulates beta -catenin.

Long Name

Axis Inhibitor 1

Alternate Names

Axin1, MGC52315

Entrez Gene IDs

8312 (Human); 12005 (Mouse); 79257 (Rat)

Gene Symbol

AXIN1

UniProt

O15169

Additional Axin-1 Products

Product Documents for Axin-1 Antibody [Alexa Fluor™ Plus 488]

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Axin-1 Antibody [Alexa Fluor™ Plus 488]


This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com.

For research use only

Related Research Areas

Wnt Family

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