GRK5 Antibody [Alexa Fluor™ Plus 594]

R&D Systems | Catalog # AF4539AFP594

R&D Systems

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Knockout Validated, Western Blot

Label

Alexa Fluor Plus 594 (Excitation = 590 nm, Emission = 618 nm)

Antibody Source

Polyclonal Goat IgG
View all GRK5 Primary Antibodies »

Product Specifications

Immunogen

E. coli-derived recombinant human GRK5

Specificity

Detects endogenous human, mouse, and rat GRK5 in Western blots.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for GRK5 Antibody [Alexa Fluor™ Plus 594]

Application
Recommended Usage

Knockout Validated

Optimal dilution of this antibody should be experimentally determined.

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Formulation

Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: GRK5

G protein-coupled receptor kinases (GRKs) are important modulators of G protein-coupled receptor (GPCR) signaling. Receptor phosphorylation by specific GRKs plays a key role in triggering rapid desensitization. The GRK family consists of 7 isoforms that share a central catalytic domain with homology to other serine/threonine kinases. The catalytic domain is flanked by an amino-terminal RGS domain of 183‑188 amino acids and a carboxyl-terminus of variable length. GRK5 is a member of the GRK4 subfamily, and is expressed in a wide variety of tissues.

Long Name

G protein-coupled Receptor Kinase 5

Alternate Names

GPRK5

Entrez Gene IDs

2869 (Human); 14773 (Mouse); 59075 (Rat)

Gene Symbol

GRK5

UniProt

P34947

Additional GRK5 Products

Product Documents for GRK5 Antibody [Alexa Fluor™ Plus 594]

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

Product Specific Notices for GRK5 Antibody [Alexa Fluor™ Plus 594]


This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com.

For research use only

Related Research Areas

Intracellular Kinases

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