Human/Mouse/Rat ILK Alexa Fluor® 750-conjugated Antibody

Catalog #: FAB4266S Datasheet / COA / SDS

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FAB4266S-100UG

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Human/Mouse/Rat ILK Alexa Fluor® 750-conjugated Antibody Summary

Species Reactivity

Human, Mouse, Rat

Specificity

Detects human, mouse, and rat ILK in Western blots.

Source

Monoclonal Mouse IgG2b Clone # 443208

Purification

Protein A or G purified

Immunogen

E. coli-derived recombinant human ILK
Met1-Lys452
Accession # Q13418

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 750 (Excitation= 749 nm, Emission= 775 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: ILK

Integrin-linked kinase (ILK) is an ankyrin repeat-containing serine/threonine protein kinase that interacts with the cytoplasmic domain of beta 1 and beta 3 integrins. ILK functions with multiple binding partners to transmit signals from the extracellular matrix to actin filaments, regulating such processes as cellular attachment, cell cycle progression, and cytoskeletal organization. ILK kinase activity is induced by PI3 kinase and negatively regulated by the tumor suppressor PTEN.

Long Name

Integrin-linked Kinase

Entrez Gene IDs

3611 (Human); 16202 (Mouse); 170922 (Rat)

Alternate Names

59 kDa serine/threonine-protein kinase; DKFZp686F1765; EC 2.7.11.1; ESTM24; ILK; ILK1; ILK-1; ILK2; ILK-2; integrin-linked kinase; integrin-linked kinase-2; integrin-linked protein kinase; p59; p59ILK