Human/Mouse/Rat PTP-MEG2 Alexa Fluor® 405-conjugated Antibody

Catalog #: FAB2668V Datasheet / COA / SDS

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FAB2668V-100UG

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Human/Mouse/Rat PTP-MEG2 Alexa Fluor® 405-conjugated Antibody Summary

Species Reactivity

Human, Mouse, Rat

Specificity

Detects human, mouse, and rat PTP-MEG2.

Source

Monoclonal Mouse IgG2b Clone # 291835

Purification

Protein A or G purified

Immunogen

E. coli-derived recombinant human PTP-MEG2
Glu2-Gln593
Accession # P43378

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 405 (Excitation= 405 nm, Emission= 421 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: PTP-MEG2

Megakaryocyte protein tyrosine phosphatase 2 (PTP-MEG2), also known as PTPN9, contains an N-terminal domain homologous to the yeast retinaldehyde binding domain Sec14p and a C-terminal phosphatase domain. The Sec14p domain targets PTP-MEG2 to the membrane of secretory vesicles, where it promotes vesicle fusion. Elevated levels of membrane-bound PTP-MEG2 activity in erythroid progenitor cells are observed in polycythemia vera and may affect responsiveness to colony stimulating factors.

Long Name

Megakaryocyte Protein Tyrosine Phosphatase 2

Entrez Gene IDs

5780 (Human); 56294 (Mouse); 266611 (Rat)

Alternate Names

EC 3.1.3.48; MEG2; protein tyrosine phosphatase, non-receptor type 9; Protein-tyrosine phosphatase MEG2; PTPase MEG2; PTPase-MEG2; PTPMEG2; PTP-MEG2; PTPN9; tyrosine-protein phosphatase non-receptor type 9