Human/Mouse/Rat Rab11A Alexa Fluor® 647-conjugated Antibody

Catalog #: FAB8978R Datasheet / COA / SDS

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FAB8978R-100UG

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Human/Mouse/Rat Rab11A Alexa Fluor® 647-conjugated Antibody Summary

Species Reactivity

Human, Mouse, Rat

Specificity

Detects human Rab-11A in direct ELISAs and Western blots.

Source

Monoclonal Mouse IgG2b Clone # 918009

Purification

Protein A or G purified

Immunogen

E. coli-derived recombinant human Rab-11A
Met1-Glu162
Accession # P62491

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 647 (Excitation= 650 nm, Emission= 668 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: Rab11A

Ras-related protein Rab11A is a 25 kDa member of the Rab family of small GTPases. With more than 40 family members, Rab proteins are regulators of vesicular transport, and their number reflects the complexity of vesicle trafficking. Rab family members cycle between an inactive GDP-bound form and an active GTP-bound form that recruits to membranes various downstream effectors directly responsible for vesicle formation, migration and fusion. Rab11A is ubiquitously expressed, with Northern blot analysis detecting highest levels in heart, and lowest levels in liver. Human Rab11A is 216 amino acids (aa) in length, with residues 214-216 removed in its mature form. Over aa 1-162, human Rab11A shares 100% identity with mouse and rat Rab11A.

Long Name

RAs Genes from Brain Protein 11A

Entrez Gene IDs

8766 (Human); 53869 (Mouse); 81830 (Rat)

Alternate Names

MGC1490; RAB 11A, member oncogene family; RAB11; Rab-11; Rab11A; RAB11A, member RAS oncogene family; YL8; YL8ras-related protein Rab-11A