Human/Mouse/Rat Syntaxin 1B Alexa Fluor® 750-conjugated Antibody

Catalog #: FAB6848S Datasheet / COA / SDS

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FAB6848S-100UG

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All Syntaxin 1B Antibodies

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Human/Mouse/Rat Syntaxin 1B Alexa Fluor® 750-conjugated Antibody Summary

Species Reactivity

Human, Mouse, Rat

Specificity

Detects human Syntaxin 1B in direct ELISAs and Western blots. In direct ELISAs, 100% cross-reactivity with recombinant human (rh) Syntaxin 1A and 1B1 is observed, and no cross-reactivity with rhSyntaxin 5, 6, 7, 8, 12, or 16 is observed.

Source

Monoclonal Mouse IgG1 Clone # 676204

Purification

Protein A or G purified

Immunogen

E. coli-derived recombinant human Syntaxin 1B
Lys2-Lys264
Accession # P61266

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 750 (Excitation= 749 nm, Emission= 775 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: Syntaxin 1B

Syntaxin 1B/STX1B is an approximately 33 kDa member of the Syntaxin family. It is a single-pass type IV transmembrane protein that is potentially involved in the docking of synaptic vesicles at presynaptic active zones. The cytoplasmic domain of Syntaxin 1B contains a coiled-coil Syntaxin domain (aa 29-180) which is implicated in the docking of synaptic vesicles with the presynaptic plasma membrane and a t-SNARE coiled coil domain (aa 191-253). Within the cytoplasmic domain, human Syntaxin 1B shares 100% aa sequence identity with mouse and rat Syntaxin 1B.

Entrez Gene IDs

112755 (Human); 56216 (Mouse); 24923 (Rat)

Alternate Names

FP17469; STX1B; STX1B1; STX1B2; Syntaxin 1B; syntaxin 1B1; syntaxin 1B2; syntaxin-1B; syntaxin-1B1; syntaxin-1B2