Human/Mouse SDPR Alexa Fluor® 594-conjugated Antibody

Catalog #: AF5759T Datasheet / COA / SDS

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AF5759T-100UG

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Human/Mouse SDPR Alexa Fluor® 594-conjugated Antibody Summary

Species Reactivity

Human, Mouse

Specificity

Detects human and mouse SDPR in Western blots.

Source

Polyclonal Goat IgG

Purification

Antigen Affinity-purified

Immunogen

E. coli-derived recombinant human SDPR
Gly2-Val180
Accession # O95810

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 594 (Excitation= 590 nm, Emission= 617 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: SDPR

SDPR (Serum deprivation response gene; also SDR and PS-p68) is a 68‑70 kDa member of the PTRF/SDPR family of proteins. It is expressed in striated muscle, platelets, and fibroblasts, and is cytosolic in location. SDPR is known to bind phosphatidylserine and form complexes with both PKC alpha and PTRF, targeting them to caveolae. Human SDPR is 425 amino acids (aa) in length. It contains an N-terminal acetylglycine, three coiled-coil regions (aa 61‑82, 125‑154, and 210‑268), and two serine phosphorylation sites at positions 287 and 293. Over aa 1‑180, human SDPR shares 91% aa identity with mouse SDPR.

Long Name

Serum Deprivation Response [Phosphatidylserine Binding Protein]

Entrez Gene IDs

8436 (Human); 20324 (Mouse); 316384 (Rat)

Alternate Names

cavin-2; Phosphatidylserine-binding protein; PS-p68; PS-p68serum deprivation response (phosphatidylserine-binding protein); SDPR; SDR; SDRphosphatidylserine binding protein; serum deprivation response (phosphatidylserine binding protein); serum deprivation response; serum deprivation-response protein