Human Nicotinamide N-Methyltransferase/NNMT Alexa Fluor® 700-conjugated Antibody

Catalog #: FAB7736N Datasheet / COA / SDS

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FAB7736N-100UG

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All Nicotinamide N-Methyltransferase/NNMT Antibodies

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Human Nicotinamide N-Methyltransferase/NNMT Alexa Fluor® 700-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human Nicotinamide N‑Methyltransferase/NNMT in direct ELISAs and Western blots.

Source

Monoclonal Mouse IgG2b Clone # 954208

Purification

Protein A or G purified

Immunogen

E.coli-derived recombinant human Nicotinamide Nâ€‘Methyltransferase/NNMT
Met1-Leu264
Accession # P40261

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 700 (Excitation= 675-700 nm, Emission= 723 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: Nicotinamide N-Methyltransferase/NNMT

Nicotinamide N-methyltransferase (NNMT) is a 264 aminoacids enzyme that catalyzes the N-methylation of nicotinamide and other pyridines to form pyridinium ions. This activity is important for biotransformation of many drugs and xenobiotic compounds. NNMT is found in human fat cells and the liver. Significant up-regulation of NNMT was found pathologies like Parkinson's disease, cancer, atherosclerosis, and liver diseases.

Long Name

Nicotinamide N-Methyltransferase

Entrez Gene IDs

4837 (Human)

Alternate Names

EC 2.1.1.1; Nicotinamide NMethyltransferase; Nicotinamide N-Methyltransferase; NNMT