Human NRG1-beta 1/HRG1-beta 1 EGF Domain Antibody

Catalog #: FAB3771V Datasheet / COA / SDS

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FAB3771V-100UG

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All Neuregulin-1 beta 1/NRG1 beta 1 Antibodies

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Human NRG1-beta 1/HRG1-beta 1 EGF Domain Antibody Summary

Species Reactivity

Human

Specificity

Detects human NRG1-beta 1 in ELISAs. Recognizes an epitope found in the EGF-like domain of NRG1‑ beta 1 (amino acids 179‑246). It also detects recombinant human SMDF (Sensory and Motor neuron-Derived Factor), but it does not recognize the EGF-like domain of human

Source

Monoclonal Mouse IgG1 Clone # 147705

Purification

Protein A or G purified

Immunogen

E. coli-derived recombinant human NRG1-Î²1/HRG1-Î²1
Ser2-Lys246
Accession # AAA58639

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 405 (Excitation= 405 nm, Emission= 421 nm)

Applications

Recommended Concentration

Sample

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: Neuregulin-1 beta 1/NRG1 beta 1

Neuregulin-1, also known as Heregulin 1, functions as a ligand for the receptor tyrosine kinases, ErbB3 and ErbB4. It exists in several different mRNA splicing variants resulting in both transmembrane and secreted forms.

Entrez Gene IDs

3084 (Human); 211323 (Mouse); 112400 (Rat)

Alternate Names

ARIA; GGF; GGF2; HGL; HRG; HRG1; HRGA; MST131; MSTP131; NDF; neuregulin 1; Neuregulin1 beta 1; Neuregulin-1 beta 1; NRG1-IT2; SMDF