Human PLD2 Alexa Fluor® 647-conjugated Antibody

Catalog #: FAB10123R Datasheet / COA / SDS

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FAB10123R-100UG

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Human PLD2 Alexa Fluor® 647-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects huma PLD2 in direct ELISAs.

Source

Monoclonal Mouse IgG2a Clone # 846224

Purification

Protein A or G purified

Immunogen

E. coli-derived recombinant human PLD2
Met1-His117
Accession # O14939

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 647 (Excitation= 650 nm, Emission= 668 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: PLD2

Phospholipase D2 (PLD2) is an enzyme encoded by the PLD2 gene. Phosphatidylcholine (PC)-specific phospholipases D (PLDs) catalyze the hydrolysis of PC to produce phosphatidic acid and choline. The Phospholipase D (PLD) lipid-signaling enzyme superfamily has long been studied for its roles in cell communication and a wide range of cell biological processes. Potent PLD2 inhibitors are available, like VU 0364739 hydrochloride (Tocris Cat. 4171) and ML 298 hydrochloride (Tocris Cat. 4895). Three different PLD2 isoforms -PLD2A, PLD2B and PLD2C- have been described, ranging from 38 to 105 KDa.

Long Name

Phospholipase D2

Entrez Gene IDs

5338 (Human); 18806 (Mouse); 25097 (Rat)

Alternate Names

Choline Phosphatase 2; HPLD2; PLD1C; PLD2