Human PRG-1/LPPR4 Alexa Fluor® 405-conjugated Antibody

Catalog #: FAB2874V Datasheet / COA / SDS

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FAB2874V-100UG

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All PRG-1/LPPR4 Antibodies

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human PRG-1/LPPR4 Alexa Fluor® 405-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects PRG‑1/LPPR4 in direct ELISAs and Western blots.

Source

Monoclonal Mouse IgG2b Clone # 368701

Purification

Protein A or G purified

Immunogen

E. coli-derived recombinant human PRGâ€‘1/LPPR4
Ser285-Asp715
Accession # AAO85400

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 405 (Excitation= 405 nm, Emission= 421 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: PRG-1/LPPR4

PRG-1 (plasticity-related gene-1) is a member of the lipid phosphate phosphatase-related protein (LPR) family. The 715 aa protein has a calculated (unglycosylated) molecular weight of 78 kDa. LPR members have six N-terminal transmembrane sequences and a C-terminal cytoplasmic domain thought to regulate phospholipid phosphatase activity. PRG-1 is expressed on axons in the hippocampus and is upregulated during axonal outgrowth. The C-terminal domain of human PRG-1 (amino acids 285‑715) shares 95% and 94% amino acid identity with mouse and rat PRG-1, respectively.

Long Name

Plasticity Related Gene 1/Lipid Phosphate Phosphatase-related Protein Type 4

Entrez Gene IDs

9890 (Human)

Alternate Names

LPPR4 lipid phosphate phosphatase-related protein type 4; LPPR4; LPR4; PHP1; PRG1; PRG-1; RP4-788L13.1