Human Pyruvate Carboxylase/PC (NP_071504.2) VersaClone cDNA

R&D Systems | Catalog # RDC3664

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Key Product Details

Species

Human

Accession Number

NP_071504.2

Background: Pyruvate Carboxylase/PC

PCB encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene. [provided by RefSeq]

Long Name

Pyruvate Carboxylase

Alternate Names

PC, PCB

Entrez Gene IDs

5091 (Human)

Gene Symbol

PC

UniProt

NP_071504.2

Additional Pyruvate Carboxylase/PC Products

Product Documents for Human Pyruvate Carboxylase/PC (NP_071504.2) VersaClone cDNA

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Product Specific Notices for Human Pyruvate Carboxylase/PC (NP_071504.2) VersaClone cDNA

For research use only

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