Human SLITRK4 Alexa Fluor® 594-conjugated Antibody

Catalog #: FAB2860T Datasheet / COA / SDS

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FAB2860T-100UG

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Human SLITRK4 Alexa Fluor® 594-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human SLITRK4 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human SLITRK1, 2, 3, or 5 is observed.

Source

Monoclonal Mouse IgG2a Clone # 319514

Purification

Protein A or G purified

Immunogen

Mouse myeloma cell line NS0-derived recombinant human SLITRK4
Asp19-Pro616
Accession # Q8IW52

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 594 (Excitation= 590 nm, Emission= 617 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: SLITRK4

Slit and Trk like gene 4 (SLITRK4) is one of six type I transmembrane (TM) proteins that belong to the SLITRK family of neurite guidance molecules. The extracellular region contains two blocks of leucine-rich repeats that are bounded by small cysteine-rich domains. The cytoplasmic region contains potential tyrosine kinase motifs reminiscent of the motifs on Trk receptors. Human SLITRK4 extracellular domain shares 98% aa sequence identity with the extracellular domains of both canine and mouse SLITRK4.

Long Name

SLIT and NTRK-like Family, Member 4

Entrez Gene IDs

139065 (Human); 245446 (Mouse)

Alternate Names

DKFZp547M2010; SLIT and NTRK-like family, member 4; SLIT and NTRK-like protein 4; slit and trk like gene 4; SLITRK4