Human Syntabulin Alexa Fluor® 647-conjugated Antibody

Catalog #: AF5544R Datasheet / COA / SDS

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AF5544R-100UG

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Human Syntabulin Alexa Fluor® 647-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human Syntabulin in direct ELISAs and Western blots.

Source

Polyclonal Goat IgG

Purification

Antigen Affinity-purified

Immunogen

E. coli-derived recombinant human Syntabulin
Gln489-Arg656
Accession # Q9NX95

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 647 (Excitation= 650 nm, Emission= 668 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: Syntabulin

Syntabulin (also Golgi-localized synaphilin-related protein) is a 70-75 kDa molecule that belongs to the syntaxin-binding and kinesin-1 family of motor adaptor proteins. It is highly spliced, with various forms associated with different tissues. In neurons, it anchors syntaxin-1 to KIF5B, creating a complex by which synaptic components can be transported to synaptic terminals. Human Syntabulin is a type II transmembrane (TM) protein 663 amino acids (aa) in length. It contains one coiled-coil region (aa 271‑353) and a TM domain between aa 606‑626. Alternate splice forms show alternate start sites at Met120 and Met207, a five aa substitution for aa 1‑8, a 16 aa insertion after Lys8, and an eight aa substitution for aa 1‑76. Over aa 486‑653, human Syntabulin shares 83% aa identity with mouse Syntabulin.

Entrez Gene IDs

55638 (Human); 319613 (Mouse); 500865 (Rat)

Alternate Names

Golgi-Localized Protein; Golgi-Localized Syntaphilin-Related Protein; GOLSYN A Protein; GOLSYN B Protein; GOLSYN C Protein; GOLSYN; Implicated In Syntaxin Trafficking In Neurons; KIAA1472; Microtubule-Associated Protein; OCSYN; SNPHL; SYBU; Syntabulin (Syntaxin-Interacting); Syntabulin; syntaphilin-like; Syntaxin-1-Binding Protein