Thymopoietin (TP alpha; also TMPO, LAP2 alpha and TPRP alpha ) is a 75 kDa member of the LEM family of molecules. It is a nucleoplasmic protein that is widely expressed in cells such as keratinocytes and thymocytes. Here, it interacts with A-type lamins and Rb/retinoblastoma protein, thus participating in cell cycle exit. Human thymopoietin is 694 amino acids (aa) in length. It contains a potential N-terminal “thymopoietin peptide” segment (aa #2-49), a BAF-binding LEM domain (aa #109-153), an NLS (aa #190-196), and a coiled-coil region (aa #558-657). Multiple splice variants exist. All contain the same 188 N-terminal amino acids. Five variants show singular 49, 157, 266, 226, and 60 aa substitutions for the C-terminal 506 amino acids. Over aa #2-187, human thymopoietin shares 93% aa identity with mouse thymopoietin.
Human Thymopoietin Alexa Fluor™ Plus 680‑conjugated Antibody
R&D Systems | Catalog # AF843AFP680
Key Product Details
Species Reactivity
Applications
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Antibody Source
Product Specifications
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Applications for Human Thymopoietin Alexa Fluor™ Plus 680‑conjugated Antibody
Western Blot
Formulation, Preparation, and Storage
Formulation
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Background: Thymopoietin
Additional Thymopoietin Products
Product Documents for Human Thymopoietin Alexa Fluor™ Plus 680‑conjugated Antibody
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Product Specific Notices for Human Thymopoietin Alexa Fluor™ Plus 680‑conjugated Antibody
This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com.
For research use only
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Protocols
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- Troubleshooting Guide: Western Blot Figures
- Western Blot Conditions
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- Western Blot Troubleshooting
- Western Blot Troubleshooting Guide
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