Human TROP-2, also called tumor associated calcium signal transducer 2 (TACSTD2), gp50 and T16, is a type I cell surface glycoprotein that is highly expressed on human carcinomas. It is related to EpCAM, also called TROP-1, gp40 and KSA. A study of these two genes suggests that TROP-2 was generated through the retropositioning of the EpCAM gene. TROP-2 and EpCAM share approximately 49% amino acid sequence identity and approximately 67% similarity. Mature human and mouse TROP-2 share 80% amino acid identity.
Human TROP-2 (NP_002344.2) VersaClone cDNA
R&D Systems | Catalog # RDC3062
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Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: TROP-2
Long Name
Tumor-associated Calcium Signal Transducer 2
Alternate Names
GA733-1, gp50, T16, TACSTD2, TROP2
Gene Symbol
TACSTD2
UniProt
Additional TROP-2 Products
Product Documents for Human TROP-2 (NP_002344.2) VersaClone cDNA
Product Specific Notices for Human TROP-2 (NP_002344.2) VersaClone cDNA
For research use only
Related Research Areas
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