Human Vasohibin Alexa Fluor® 532-conjugated Antibody

Catalog #: FAB33191X Datasheet / COA / SDS

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FAB33191X-100UG

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All Vasohibin Antibodies

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Human Vasohibin Alexa Fluor® 532-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human Vasohibin in direct ELISAs and Western blots.

Source

Monoclonal Mouse IgG2b Clone # 411208

Purification

Protein A or G purified

Immunogen

Mouse myeloma cell line NS0-derived recombinant human Vasohibin isoform 1
Pro2-Val365
Accession # Q7L8A9

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 532 (Excitation= 534 nm, Emission= 553 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: Vasohibin

Vasohibin is an endothelium-derived negative feedback regulator of angiogenesis. The 365 amino acid (aa), 44 kDa human Vasohibin shows 93% aa identity with mouse Vasohibin. Vasohibin has no canonical signal sequence, but the full-length form is only associated with cells, while N-terminally cleaved, active 42 kDa and 36 kDa forms are both cell-associated and secreted. Minor amounts of C-terminally cleaved 27 kDa form are inactive and lack the C-terminal heparin-binding basic domain. Vasohibin expression is upregulated by VEGF and FGF‑2, but this can be modulated by IL-1, TNF‑ alpha, or IFN‑ gamma.

Entrez Gene IDs

22846 (Human); 238328 (Mouse)

Alternate Names

KIAA1036; KIAA1036vasohibin-1; VASH; VASH1; vasohibin 1; Vasohibin