Human Vasohibin Isoform 1 Alexa Fluor® 700-conjugated Antibody

Catalog #: AF3319N Datasheet / COA / SDS

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AF3319N-100UG

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Human Vasohibin Isoform 1 Alexa Fluor® 700-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human Vasohibin Isoform 1 in direct ELISAs and Western blots.

Source

Polyclonal Goat IgG

Purification

Antigen Affinity-purified

Immunogen

Mouse myeloma cell line NS0-derived recombinant human Vasohibin Isoform 1
Pro2-Val365
Accession # Q7L8A9

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 700 (Excitation= 675-700 nm, Emission= 723 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: Vasohibin

Vasohibin is a secreted endothelium-derived negative feedback regulator of angiogenesis whose expression in endothelial cells is induced by proangiogenic growth factors such as VEGF and FGF-2. It is synthesized as a 365 amino acid residue protein that lacks a canonical signal peptide. As a result of proteolytic cleavage, multiple distinct molecular weight forms can be detected when Vasohibin is expressed on endothelial cells. Human and mouse Vasohibin share 93% amino acid sequence identity. Two splice variants of human Vasohibin have been reported.

Entrez Gene IDs

22846 (Human); 238328 (Mouse)

Alternate Names

KIAA1036; KIAA1036vasohibin-1; VASH; VASH1; vasohibin 1; Vasohibin